Phenobarbital is a long-acting barbiturate. Start studying Phenobarbital. Phenobarbital produces a depressant effect on the CNS through actions at GABA A receptors (McNamara, 2011). Phenobarbitone : Therapeutic uses, Dosage & Side Effects Phenobarbitone (Phenobarbital or phenobarb) is a long acting Barbiturate, used for short-term treatment of sleeplessness, the relief of anxiety, tension, and fear, and the treatment of certain types of seizures, especially in emergency situations. Generic Name Phenobarbital Trade/Brand Name Luminal Indication Seizures Sedation Action Depresses sensory cortex Decrease motor activity Alters cerebellar function Produces drowsiness, sedation, hypnosis Therapeutic Class Sedative Hypnotic Anticonvulsant Pharmacologic Class Long-acting barbiturate Nursing Considerations Contraindicated Airway obstruction Severe renal disorders … Infants and children: 15-20 mg/kg IV infused at a rate not to exceed 2 mg/kg/min; not to exceed 1000 mg/dose . 30 mg/min. It depresses the sensory cortex, reduces motor activity, changes cerebellar function and produces drowsiness, sedation and hypnosis. Phenobarbital, also known as phenobarbitone in British English and by the brand name Luminal, is a long-acting psychoactive drug of the barbiturate class which produces powerful anxiolytic, hypnotic, muscle relaxant and amnesic effects. Phenobarbital is a barbiturate, a … Phenobarbital (fee-noe-bar-bih-tal) is a generic medication manufactured by several companies. Data sources include IBM Watson Micromedex (updated 1 Apr 2021), Cerner Multum™ (updated 5 Apr 2021), … Phenobarbital acts on GABAA receptors, increasing synaptic inhibition. ACTIVE LEARNING TEMPLATE: Medication STUDENT NAME _ Phenobarbital Barbiturates MEDICATION _ ATI 16 REVIEW MODULE CHAPTER This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Status Epilepticus. In 1912, two independent teams of chemists created the drug under the name of Luminal. Phenobarbital is a long-acting barbiturate that has sedative, hypnotic, and anticonvulsant effects. Its anticonvulsant property is exhibited at high doses. Phenobarbital, the longest-acting barbiturate, is used for its anticonvulsant and sedative-hypnotic properties in the management of all seizure disorders except absence (petit mal). Phenobarbital acts on GABAA receptors, increasing synaptic inhibition. Phenobarbital is classified as FDA pregnancy risk category D. Use of phenobarbital during pregnancy may cause major fetal malformations, hemorrhage at birth, and addiction. May repeat with 5-10 mg/kg bolus dose after 15-30 min PRN; not to exceed cumulative dose of 40 mg/kg The metabolite of chloral hydrate exerts its pharmacological properties via enhancing the GABA receptor complex and therefore is similar in action to benzodiazepines, nonbenzodiazepines and barbiturates. Learn vocabulary, terms, and more with flashcards, games, and other study tools. Phenobarbital is used medically as an anticonvulsant, and occasionally in the short term treatment of insomnia. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Like other barbiturates, phenobarbital depresses the sensory cortex, decreases motor activity, and alters cerebellar function. View Phenobarbital .pdf from CNURSING 340 at Long Island University. It can be moderately addictive, as chronic use is known to cause dependency and withdrawal symptoms. 60 kg: IV rate at . Mechanism of action. It may also be used for other conditions as determined by your … Additionally, a retrospective study revealed that in utero exposure to phenobarbital was associated with intelligence deficits. It is the oldest epilepsy medicine still in use.
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