Good to excellent results were reported1,4,5 in dogs, cats and horses given Acepromazine Injection for restraint during examination, treatment and minor surgery and for preanesthetic sedation. More Info; Compare; ON PROMOTION; Login {{promo.PromoName}} {{promo.PromoText}} {{promo.StartDate | date : 'MM/dd/yyyy'}} - {{promo.EndDate | date : 'MM/dd/yyyy'}} Apr- 2021 Mar- 2021 Feb- 2021 Jan- 2021 Dec- 2020 Nov- 2020 Oct- 2020 Sep- … Side Effects of Aceproject for Dogs. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Acepromazine is a commonly used tranquilizer/sedative in dogs, cats, horses, and other animals. 1) Acepromazine (only) a) General information i) A phenothiazine tranquilizer (1) Acepromazine has no direct analgesic properties ii) Acepromazine can be used alone, as a premedicant. 8. Acepromazine Maleate Injection, 10 mg/ml is a sterile solution for intravenous, intramuscular or subcutaneous injection. It has been postulated that such paralysis may occur when a tranquilizer is used in conjunction with testosterone (or in stallions). Acepromazine Injection (acepromazine maleate, USP), a potent neuroleptic agent with a low order of toxicity, is of particular value in the tranquilization of dogs, cats and horses. In this case series, OTM DM (mean dose of 32.6 μg/kg body weight) was … . Options: 50ml vial - 10mg/ml. When given, the dosage should be carefully limited to the minimum necessary for the desired effect. Espèces cibles. Acepromazine Injection may be given intravenously, intramuscularly or subcutaneously. Eviter les procédures douloureuses et prendre les précautions habituelles lors de la manipulation des animaux tranquillisés. In dogs, the drug reportedly4 helps control convulsions associated with distemper. Vet. The dog sedative acepromazine works well for most dogs and is relatively safe to use Dosage is determined by body weight with most dogs receiving one milligram or less of medication per pound. In dogs, the drug reportedly4 helps control convulsions associated with distemper. Acepromazine maleate injection is particularly useful as a preanesthetic agent (1) to enhance and prolong the effects of barbiturates, thus reducing the requirements for general anesthesia; (2) as an adjunct to surgery under local anesthesia. Quantity Add to Cart Email this product to a friend Veterinarian Prescription (RX) Required Free Shipping on orders over $75 Low Price Match Guarantee. Keeping your dog calm during his or her most excitable moments, especially when traveling, is an essential part of successful pet ownership. Le proto-cole anesthésique était évalué en termes de Other pressor amines, such as norepinephrine or phenylephrine, are the drugs of choice. It is important to note that when used alone, acepromazine is not an effective pain reliever and does little if anything to relieve a pets anxiety or fear. : Clinical Reports to Ayerst Laboratories, 1963. Every effort has been made to ensure the accuracy of the Acepromazine Injection information published above. Injectable dexmedetomidine (DM) is widely used for sedation, restraint, anxiolysis, and analgesia in veterinary medicine. Your vet may adjust the dosage, however, based on … Every effort has been made to ensure the accuracy of the Acepromazine maleate Injection information published above. Among all of the various types of this polysaccharide, κ-Carrageenan has the ability of gel forming with more firm structure. The following schedule may be used as a guide to IV, IM or SC injections: IV doses should be administered slowly, and a period of at least 15 minutes should be allowed for the drug to take full effect. Foley, J.T. 4.2. In both dogs and cats, good to excellent results were obtained4 when acepromazine maleate tablets were used to control nervousness, excessive vocalization, neurotic and excitable behavior, vomiting associated with motion sickness, coughing and itching caused by dermatitis. Indications: Dogs and Cats: Acepromazine Injection can be used as an aid in controlling intractable animals during examination, treatment, grooming, x-ray and minor surgical procedures; to alleviate itching as a result of skin irritation; as an antiemetic to control vomiting associated with motion sickness. Another group of four dogs, given gradually increasing oral doses up to a level of 220 mg/kg daily and reaching a total daily dose of 2.2 g per dog, showed some signs of pulmonary edema and hyperemia of the internal organs, but no animal died. Vet. Propriétés / Effets . Unfortunately, many dogs tend to get over-enthused about certain events. *RX* Federal law restricts this drug to use by or on the order of a licensed veterinarian. Vet. Supplied By: Covetrus (136145) SKU 003845. Select one or more newsletters to continue. : Clinical Reports to Ayerst Laboratories, 1963. Dogs: 0.25-0.5 mg/lb of body weight. Auch auf Reisen oder zur Milderung der Symptome von Reisekrankheit hat sich das Medikament bewährt. Solution injectable. Another group of four dogs, given gradually increasing oral doses up to a level of 220 mg/kg daily and reaching a total daily dose of 2.2 g per dog, showed some signs of pulmonary edema and hyperemia of the internal organs, but no animal died. Available for Android and iOS devices. Acepromazine is metabolized by the liver and eliminated by the kidneys and as a result has a longer half-life in young animals. The following schedule may be used as a guide to IV, IM or SC injections. The cause of this side reaction has not been determined. It may be used in conjunction with atropine as a pre-operative medication for anxiety and for its antidysrhythmic effects. En cas d’antécédent de ce type, de syncope ou de risque suspecté en raison d’une arythmie … 40:45 (Nov.1) 1959. Indications: Dogs and Cats: Acepromazine Injection can be used as an aid in controlling intractable animals during examination, treatment, grooming, x-ray and minor surgical procedures; to alleviate itching as a result of skin irritation; as an antiemetic to … Dosage pour les chiens. Baker, J.M. Ford, R.W. Data sources include IBM Watson Micromedex (updated 1 Apr 2021), Cerner Multum™ (updated 5 Apr 2021), ASHP (updated 6 Apr 2021) and others. It decreases anxiety, causes central nervous system depression, and a drop in blood pressure and heart rate. Other pressor amines, such as norepinephrine or phenylephrine, are the drugs of choice. Acepromazine may be taken with food to avoid stomach upset. The usual injectable dose is 0.01 to 0.1 mg per pound (0.02 to 0.2 mg/kg). Particularly useful when used in conjunction with local anesthesia for firing, castration, neurectomy, removal of skin tumors, ocular surgery and applying casts. Hypotension can occur after rapid intravenous injection causing cardiovascular collapse. Animal safety: Acute and chronic toxicity studies have shown a very low order of toxicity. Nous avons évalué l’efficacité antiémétique et l’inconfort en réponse à une injection SC de MRP [1 mg/kg de poids corporel (PC)], de MCP (0,5 mg/kg PC) et d’une solution saline normale (SAL; 0,1 mL/kg PC) administrée à 63 chiens, 45 minutes avant la morphine (0,5 mg/kg PC) et l’acépromazine (0,05 mg/kg PC). Pharmacology Reports, ClinByla Laboratories, Paris, France. It is a powerful neuroleptic agent that boasts a low order of toxicity, which is particularly valuable in tranquilizing horses, cats, and dogs. As a general rule, the dosage requirement in mg/lb of body weight decreases as the weight of the animal increases. Dunkin, T.E. : Clinical Reports to Ayerst Laboratories, 1963. Never give the same dose by injection that one would give orally. Such cases have occurred following the use of Acepromazine maleate injection. It may be injected intravenously, intramuscularly or subcutaneously. : Paper presented at the Ontario Veterinary Association meeting, held in Toronto, Canada, 1958. L’injection d’acépromazine peut provoquer une attaque, une faible dose doit être utilisée. However, it remains the responsibility of the readers to familiarize themselves with the product information contained on the US product label or package insert. Bei selbst bei ansonsten ruhigen Tieren oft schwer dur… Acepromazine maleate injection may be given intravenously, intramuscularly or subcutaneously. Acepromazine Maleate Tablets and Injection is used in controlling intractable animals during examination, treatment, grooming, x-ray and minor surgical procedures. Epinephrine is contraindicated for treatment of acute hypotension produced by phenothiazine-derivative tranquilizers since further depression of blood pressure can occur. Total Ear Canal Ablation and Ventral Bulla Osteotomy (TECA) for End-Stage Ears in Dogs and Cats Do not use in conjunction with organophosphorus vermifuges or ectoparasiticides, including flea collars. To prepare the injectable hydrogel, two other polymers rather than chitosan were also used . Other practitioners7,8 found the drug useful as a preanesthetic sedative for nervous or aggressive horses, but it had to be administered while the animals were quiet and not in an excited state. In horses, paralysis of the retractor penis muscle has been associated with the use of phenothiazine-derivative tranquilizers. We comply with the HONcode standard for trustworthy health information -, Acepromazine maleate Injection Indications, Warnings and cautions for Acepromazine maleate Injection, Direction and dosage information for Acepromazine maleate Injection. vet., Acépromazine, solution injectable. Accidental intracarotid injection in horses can produce clinical signs ranging from disorientation to convulsive seizures and death. Chez certains chiens, notamment le boxer et les races de chien brachycéphales, une perte de connaissance ou une syncope spontanée peuvent survenir à cause du bloc sinoauriculaire provoqué par un tonus vagal excessif. To report suspected adverse reactions, to obtain a Safety Data Sheet or for technical assistance, call 1-855-724-3461. dosage oral acépromazine typique est de 1 à 3 mg / kg (0,5 à 1,5 mg par livre) et le dosage injectable est de 0,02 à 0,2 mg / kg (0,01 à 0,1 mg par livre). Available for Android and iOS devices. 50ml Vial. Acepromazine also blocks alpha-adrenergic receptors. Acepromazine is one of the most commonly used tranquilizers for dogs and cats. However, it is more effective to use Acepromazine in combination with an opioid narcotic agent. Updated: 2021-04-01. View Larger Image. Do not use with procaine hydrochloride. : Pharmacology Report, Ayerst Laboratories, 1958. Dabei ist seine lange Wirksamkeit von Vorteil und dass Acepromazin keine Ataxien verursacht. Pract. Page Number (Desk, Pocket): 353, 478; Change: Below phonetic spelling--> Change Dopamine-2 Agonist to Dopamine-2 Antagonist; Doxycycline . Selbst Psychosen und Verhaltensstörungen lassen sich mit Acepromazin positiv beeinflussen. Chronic toxicity: Tests3 in rats revealed no deleterious effects on renal or hepatic function or on hemopoietic activity. Its rapid action and lack of hypnotic effect are added advantages. 40:46 (Nov. 1) 1959. If your veterinarian has prescribed Acepromazine for your dog, you might be worried and wondering whether it’s a safe option. Acepromazinum 10 mg ut Acepromazini hydrogenomaleas, Aqua ad injectabilia ad 1 ml. Veterinarians typically prescribe acepromazine to quiet agitated animals or use it as a part of an anesthetic protocol. A potent neuroleptic agent with a low order of toxicity, is of particular value in the tranquilization of dogs, cats and horses. Oral transmucosal dexmedetomidine (OTM DM) has been evaluated in horses, cats, and humans, but not in dogs. Tranquilizers can produce prolonged depression or motor restlessness when given in excessive amounts or when given to sensitive animals. Distributed by: Covetrus North America, 400 Metro Place North, Dublin, OH 43017, Copyright © 2021 Animalytix LLC. 4.1. 7. According to Baker,1 the scope of possible applications for this compound in veterinary practice is only limited by the imagination of the practitioner. OSHA Specifically Regulated Substances (29 CFR 1910.1001-1050) Not listed. Federal law restricts this drug to use by or on the order of a licensed veterinarian. Tranquilizers should be administered in smaller doses and with greater care during general anesthesia and also to animals exhibiting symptoms of stress, debilitation, cardiac disease, sympathetic blockade, hypovolemia or shock. In a trial9 on more than 200 horses with a wide variety of disorders, Acepromazine maleate injection proved to be both effective and safe. Pract. Du liquide synovial a été prélevé de manière aseptique à partir d’une articulation du carpe et du tarse de chaque porc anesthésié. Chez les chevaux, les chiens et les chats : - Tranquillisation et pré-anesthésie. Phenothiazines may potentiate the toxicity of organophosphates and the activity of procaine hydrochloride. Data sources include IBM Watson Micromedex (updated 1 Apr 2021), Cerner Multum™ (updated 5 Apr 2021), ASHP (updated 6 Apr 2021) and others. Do not use in conjunction with organophosphorus vermifuges or ectoparasiticides, including flea collars. 5. Price: $26.95. It acts rapidly, exerting a prompt and pronounced calming effect. According to Baker,1 the scope of possible applications for this compound in veterinary practice is only limited by the imagination of the practitioner. Acepromazine [10-[3-(dimethylamino) propyl] phenothiazin-2-yl-methyl ketone] Maleate, USP has the following chemical structure: Acepromazine maleate injection has a depressant effect on the central nervous system and, therefore, causes sedation, muscular relaxation and a reduction in spontaneous activity. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Indications d'utilisation, en spécifiant les espèces cibles. Acepromazine maleate injection may be given intravenously, intramuscularly or subcutaneously. A sterile solution for IV, IM or SQ injection in dogs as an aid in tranquilization. Therefore, do not use Acepromazine maleate injection to control tremors associated with organic phosphate poisoning. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Many of them also struggle with car sickness or vomiting in general. To report suspected adverse reactions, to obtain a Material Safety Data Sheet or for technical assistance, call 1-866-638-2226. Made by VetOne. If you miss a dose, take the missed dose as soon as you remember. However, it remains the responsibility of the readers to familiarize themselves with the product information contained on the US product label or package insert. Luckily, there ar Ford, R.W. In several groups of two male and two female beagle hounds treated for six months with daily oral doses of 20 to 40 mg/kg, no untoward effects were encountered. 4. Contre-indications . Also, oral dosage is larger in quantity compared to injectable dosage. It has been postulated that such paralysis may occur when a tranquilizer is used in conjunction with testosterone (or in stallions). Acepromazine Injectable. Indications: dogs and Cats: Acepromazine maleate injection can be used as an aid in controlling intractable animals during examination, treatment, grooming, x-ray and minor surgical procedures; to alleviate itching as a result of skin irritation; as an antiemetic to control vomiting associated with motion sickness. Ce médicament doit être utilisé avec précautions chez les races de chien brachycéphales, par exemple le boxer. Stegen, M.G. Acepromazine Injection can be used as an aid in controlling intractable animals during examination, treatment, grooming, x-ray and minor surgical procedures; to alleviate itching as a result of skin irritation; as an antiemetic to control vomiting associated with motion sickness. Baker, J.M. Acepromazine Injection, like other phenothiazine derivatives, is detoxified in the liver; therefore, it should be used with caution in animals with a previous history of liver dysfunction or leukopenia. Acepromazine is also commonly given as a preanesthetic agent. 4. Acepromazine [10-[3-(dimethylamino) propyl] phenothiazin-2-yl-methyl ketone] Maleate, USP has the following chemical structure: Acepromazine Injection has a depressant effect on the central nervous system and, therefore, causes sedation, muscular relaxation and a reduction in spontaneous activity. Change: Storage/Stability--> Dimenhydrinate products should be stored at room temperature; avoid freezing [REMOVE and] injectable products. 4. 2. Canine and feline. Baldwin, R.: in Equine Panel Report, Mod. In several groups of two male and two female beagle hounds treated for six months with daily oral doses of 20 to 40 mg/kg, no untoward effects were encountered. AceProject pour les chiens est disponible en comprimés (5mg, 10mg, 25mg) et sous forme injectable (10ml / mg). Accidental intracarotid injection in horses can produce clinical signs ranging from disorientation to convulsive seizures and death. Vet. Hypotension can occur after rapid intravenous injection causing cardiovascular collapse. Hematologic studies and urinalysis gave values within normal limits. : in Equine Panel Report, Mod. Its rapid action and lack of hypnotic effect are added advantages. Whether being used as a pre-anesthetic or as an induction anesthetic, these are great anesthetic drug choices and, when used properly in conjunction with other appropriate drugs, … 6. 2. Good to excellent results were reported1,4,5 in dogs, cats and horses given Acepromazine maleate injection for restraint during examination, treatment and minor surgery and for preanesthetic sedation. Pack Type Vial. : Pharmacology Report, Ayerst Laboratories, 1958. Composition. Veterinary Medical Records, Ayerst Laboratories. Animal Safety: Acute and chronic toxicity studies have shown a very low order of toxicity. L'acépromazine possède peu, voire pas d'effet analgésique. Acepromazine Injectable requires a prescription from your veterinarian. The cause of this side reaction has not been determined. 4.3. Other practitioners7,8 found the drug useful as a preanesthetic sedative for nervous or aggressive horses, but it had to be administered while the animals were quiet and not in an excited state. Bauman, W.G. Therefore, do not use Acepromazine Injection (acepromazine maleate, USP) to control tremors associated with organic phosphate poisoning. It is also available as a tablet to be given by mouth.
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